Would love to see this supported, especially for people that are handed a DB to read from that we didn't create ourselves... critical for a Windows Phone application I'm working on.

There are a few problems when trying to run under Mono (2.10.2, most recent official). It would be great to have Mono support, so that the platform-independence transfers over to C#-Sqlite

I think that SQLite is in the process of implementing the next version of FTS (4); That would be a good time to look at implementation

This would greatly simplify deployment.

Bindings for the OSS System.Data.Sqlite (http://sqlite.phxsoftware.com/) would allow a lot of existing code to work with CS-Sqlite, and also provide a uniform API for sqlite across the major mobile platforms - currently Mono provides an ADO.NET API for iOS and Android, and it would be great if Windows Phone 7 could also be added to the list.

I would be happy to see you having a Compact Framework version.

Not Windows Phone 7!
"Old" CF2.0 or CF3.5 version for older devices.

I think can be a very good idea EF Support.

Very useful for GPS and GIS-related applications

It would be nice to have a portable class library project for csharp-sqlite. This could faciliate the code in some places where there are a lot of compiler directives in the code.

Literature:
http://msdn.microsoft.com/en-us/library/gg597391.aspx
http://slodge.blogspot.de/2012/04/using-portable-library-tools-for.html